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GHS precautionary statement

P280: Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/

  • P280
  • Prevention

P280 says: “Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/”. It is a prevention statement. P200 series: actions to take before and during use to prevent or minimise harm, such as avoiding ignition sources, using ventilation and wearing protective equipment.

The dots (...) mark a blank that the supplier fills in with specific information, such as the equipment, material or temperature that applies to the product.

About the prevention group

P200 series: actions to take before and during use to prevent or minimise harm, such as avoiding ignition sources, using ventilation and wearing protective equipment. See all precautionary statements for the full list.

Hazards that call for P280

The GHS data recommends P280 for these hazard statements.

CodeStatementHazard class and categorySignal word
H201Explosive; mass explosion hazard Deleted
Explosives — Div 1.1
Danger
H202Explosive; severe projection hazard Deleted
Explosives — Div 1.2
Danger
H203Explosive; fire, blast or projection hazard Deleted
Explosives — Div 1.3
Danger
H204Fire or projection hazard
Explosives — Category 2B
Explosives — Category 2C
Warning
H205May mass explode in fire Deleted
Explosives — Div 1.5
Danger
H206Fire, blast or projection hazard; increased risk of explosion if desensitizing agent is reduced
Desensitized explosives — Category 1
Danger
H207Fire or projection hazard; increased risk of explosion if desensitizing agent is reduced
Desensitized explosives — Category 2
Desensitized explosives — Category 3
Danger
H208Fire hazard; increased risk of explosion if desensitizing agent is reduced
Desensitized explosives — Category 4
Warning
H209Explosive
Explosives — Category 1
Explosives — Category 2A
Danger
H210Very sensitive
Explosives — Category 1
Danger
H211Maybe sensitive
Explosives — Category 1
Danger
H220Extremely flammable gas
Flammable gases — 1A: Flammable gas, Pyrophoric gas, Chemically unstable gas A,B
Danger
H224Extremely flammable liquid and vapor
Flammable liquids — Category 1
Danger
H225Highly Flammable liquid and vapor
Flammable liquids — Category 2
Danger
H226Flammable liquid and vapor
Flammable liquids — Category 3
Warning
H227Combustible liquid
Flammable liquids — Category 4
Warning
H228Flammable solid
Flammable solids — Category 1
Flammable solids — Category 2
Danger
H232May ignite spontaneously if exposed to air
Flammable gases — 1A, Pyrophoric gas
Danger
H240Heating may cause an explosion
Self-reactive substances and mixtures; Organic peroxides — Type A
Danger
H241Heating may cause a fire or explosion
Self-reactive substances and mixtures; Organic peroxides — Type B
Danger
H242Heating may cause a fire
Self-reactive substances and mixtures; Organic peroxides — Type C, D
Self-reactive substances and mixtures; Organic peroxides — Type E, F
Danger
H250Catches fire spontaneously if exposed to air
Pyrophoric liquids — Category 1
Pyrophoric solids — Category 1
Danger
H251Self-heating; may catch fire
Self-heating substances and mixtures — Category 1
Danger
H252Self-heating in large quantities; may catch fire
Self-heating substances and mixtures — Category 2
Warning
H260In contact with water releases flammable gases which may ignite spontaneously
Substances and mixtures which in contact with water, emit flammable gases — Category 1
Danger
H261In contact with water releases flammable gas
Substances and mixtures which in contact with water, emit flammable gases — Category 2
Substances and mixtures which in contact with water, emit flammable gases — Category 3
Danger
H271May cause fire or explosion; strong Oxidizer
Oxidizing liquids; Oxidizing solids — Category 1
Danger
H272May intensify fire; oxidizer
Oxidizing liquids; Oxidizing solids — Category 2
Oxidizing liquids; Oxidizing solids — Category 3
Danger
H310Fatal in contact with skin
Acute toxicity, dermal — Category 1, 2
Danger
H311Toxic in contact with skin
Acute toxicity, dermal — Category 3
Danger
H312Harmful in contact with skin
Acute toxicity, dermal — Category 4
Warning
H314Causes severe skin burns and eye damage
Skin corrosion/irritation — Category 1, 1A, 1B, 1C
Danger
H315Causes skin irritation
Skin corrosion/irritation — Category 2
Warning
H317May cause an allergic skin reaction
Sensitization, Skin — Category 1, 1A, 1B
Warning
H318Causes serious eye damage
Serious eye damage/eye irritation — Category 1
Danger
H319Causes serious eye irritation
Serious eye damage/eye irritation — Category 2A
Warning
H340May cause genetic defects
Germ cell mutagenicity — Category 1, 1A, 1B
Danger
H341Suspected of causing genetic defects
Germ cell mutagenicity — Category 2
Warning
H350May cause cancer
Carcinogenicity — Category 1, 1A, 1B
Danger
H350iMay cause cancer by inhalation
Carcinogenicity — Category 1, 1A, 1B
Danger
H351Suspected of causing cancer
Carcinogenicity — Category 2
Warning
H360May damage fertility or the unborn child
Reproductive toxicity — Category 1, 1A, 1B
Danger
H360DMay damage the unborn child
Reproductive toxicity — Category 1, 1A, 1B
Danger
H360DfMay damage the unborn child; Suspected of damaging fertility
Reproductive toxicity — Category 1, 1A, 1B
Danger
H360FMay damage fertility
Reproductive toxicity — Category 1, 1A, 1B
Danger
H360FDMay damage fertility; May damage the unborn child
Reproductive toxicity — Category 1, 1A, 1B
Danger
H360FdMay damage fertility; Suspected of damaging the unborn child
Reproductive toxicity — Category 1, 1A, 1B
Danger
H361Suspected of damaging fertility or the unborn child
Reproductive toxicity — Category 2
Warning
H361dSuspected of damaging the unborn child
Reproductive toxicity — Category 2
Warning
H361fSuspected of damaging fertility
Reproductive toxicity — Category 2
Warning
H361fdSuspected of damaging fertility; Suspected of damaging the unborn child
Reproductive toxicity — Category 2
Warning

Chemicals using P280

111 chemicals in our database (showing the first 60 alphabetically). Classification comes from each chemical's primary GHS source, so a supplier's SDS may differ.

(+-)-2-Butanol
CAS 78-92-2 · Warning
1-Butanol
CAS 71-36-3 · Danger
1-Decanol
CAS 112-30-1 · Warning
1-Dodecanol
CAS 112-53-8 · Warning
1-Nonanol
CAS 143-08-8 · Warning
1-Octanol
CAS 111-87-5 · Warning
1-Pentanol
CAS 71-41-0 · Warning
1-Propanol
CAS 71-23-8 · Danger
1-Tetradecanol
CAS 112-72-1 · Warning
1,3-Butadiene
CAS 106-99-0 · Danger
1,3-Butanediol
CAS 107-88-0 · Warning
1,3-Propanediol
CAS 504-63-2 · Warning
2-Butoxyethanol
CAS 111-76-2 · Danger
2-Ethylhexanol
CAS 104-76-7 · Warning
2-Octanol
CAS 123-96-6 · Danger
2-Pentanol
CAS 6032-29-7 · Warning
2,3-Butanediol
CAS 513-85-9 · Warning
Acetic Acid
CAS 64-19-7 · Danger
Acetone
CAS 67-64-1 · Danger
Acetonitrile
CAS 75-05-8 · Danger
Acetylene
CAS 74-86-2 · Danger
Acrylamide
CAS 79-06-1 · Danger
Acrylic Acid
CAS 79-10-7 · Danger
Allyl Alcohol
CAS 107-18-6 · Danger
Ammonia
CAS 7664-41-7 · Danger
Ammonium Hydroxide
CAS 1336-21-6 · Danger
Aniline
CAS 62-53-3 · Danger
Benzene
CAS 71-43-2 · Danger
Benzyl Alcohol
CAS 100-51-6 · Warning
Bisphenol A
CAS 80-05-7 · Danger
Borax (B4Na2O7.10H2O)
CAS 1303-96-4 · Danger
Boric Acid
CAS 10043-35-3 · Danger
Butane
CAS 106-97-8 · Danger
Butyl Acetate
CAS 123-86-4 · Warning
Cadmium
CAS 7440-43-9 · Danger
Calcium Chloride
CAS 10043-52-4 · Warning
Calcium Hydroxide
CAS 1305-62-0 · Danger
Calcium Oxide
CAS 1305-78-8 · Danger
Carbon Monoxide
CAS 630-08-0 · Danger
Cetyl Alcohol
CAS 36653-82-4 · Warning
Chlorine
CAS 7782-50-5 · Danger
Chloroform
CAS 67-66-3 · Danger
Chromium Trioxide
CAS 1333-82-0 · Danger
Citric Acid
CAS 77-92-9 · Warning
Copper Sulfate
CAS 7758-98-7 · Warning
Cyclohexane
CAS 110-82-7 · Danger
Cyclohexanol
CAS 108-93-0 · Warning
Dichloromethane
CAS 75-09-2 · Warning
Diethyl Ether
CAS 60-29-7 · Danger
Dimethyl Sulfoxide
CAS 67-68-5 · Warning
Dimethylformamide
CAS 68-12-2 · Danger
Diphenylmethane diisocyanate
CAS 101-68-8 · Danger
Dipropylene Glycol
CAS 25265-71-8 · Danger
Epichlorohydrin
CAS 106-89-8 · Danger
Ethanol
CAS 64-17-5 · Danger
Ethanolamine
CAS 141-43-5 · Danger
Ethyl Acetate
CAS 141-78-6 · Danger
Ethylene Oxide
CAS 75-21-8 · Danger
Formaldehyde
CAS 50-00-0 · Danger
Furfuryl Alcohol
CAS 98-00-0 · Danger

P280 frequently asked questions

What does P280 mean?

P280 says: "Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/". It is a prevention precautionary statement in the Prevention (P200 series).

Which hazards call for P280?

In the GHS data, P280 is recommended for hazard statements H201, H202, H203, H204, H205, H206, H207, H208, H209, H210, H211, H220, H224, H225, H226, H227, H228, H232, H240, H241, H242, H250, H251, H252, H260, H261, H271, H272, H310, H311, H312, H314, H315, H317, H318, H319, H340, H341, H350, H350i, H351, H360, H360D, H360Df, H360F, H360FD, H360Fd, H361, H361d, H361f, H361fd.

What type of statement is P280?

P280 is in the Prevention (P200 series). P200 series: actions to take before and during use to prevent or minimise harm, such as avoiding ignition sources, using ventilation and wearing protective equipment.

Precautionary statements are general recommendations. Follow the specific instructions on your product's label and safety data sheet.

https://pubchem.ncbi.nlm.nih.gov/ghs/ghscode_10.txt (UN GHS Revision 10, retrieved 2026-10-12)