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GHS precautionary statement

P370+P378: In case of fire: Use ... to extinguish

  • P370+P378
  • Response
  • Combined statement

P370+P378 says: “In case of fire: Use ... to extinguish”. It is a response statement that combines P370, P378. P300 series: what to do after a spill, exposure or fire, including first-aid steps and when to call a poison center or doctor.

The dots (...) mark a blank that the supplier fills in with specific information, such as the equipment, material or temperature that applies to the product.

About the response group

P300 series: what to do after a spill, exposure or fire, including first-aid steps and when to call a poison center or doctor. See all precautionary statements for the full list.

Component statements

A combined statement joins single statements that are printed as one sentence. This one is made of:

CodeStatement
P370In case of fire:
P378Use ... to extinguish.

Hazards that call for P370+P378

The GHS data recommends P370+P378 for these hazard statements.

CodeStatementHazard class and categorySignal word
H224Extremely flammable liquid and vapor
Flammable liquids — Category 1
Danger
H225Highly Flammable liquid and vapor
Flammable liquids — Category 2
Danger
H226Flammable liquid and vapor
Flammable liquids — Category 3
Warning
H227Combustible liquid
Flammable liquids — Category 4
Warning
H228Flammable solid
Flammable solids — Category 1
Flammable solids — Category 2
Danger
H242Heating may cause a fire
Self-reactive substances and mixtures; Organic peroxides — Type C, D
Self-reactive substances and mixtures; Organic peroxides — Type E, F
Danger
H250Catches fire spontaneously if exposed to air
Pyrophoric liquids — Category 1
Pyrophoric solids — Category 1
Danger
H260In contact with water releases flammable gases which may ignite spontaneously
Substances and mixtures which in contact with water, emit flammable gases — Category 1
Danger
H261In contact with water releases flammable gas
Substances and mixtures which in contact with water, emit flammable gases — Category 2
Substances and mixtures which in contact with water, emit flammable gases — Category 3
Danger
H271May cause fire or explosion; strong Oxidizer
Oxidizing liquids; Oxidizing solids — Category 1
Danger
H272May intensify fire; oxidizer
Oxidizing liquids; Oxidizing solids — Category 2
Oxidizing liquids; Oxidizing solids — Category 3
Danger
H282Extremely flammable chemical under pressure: may explode if heated
Chemicals under pressure — Category 1
Danger
H283Flammable chemical under pressure: may explode if heated
Chemicals under pressure — Category 2
Warning

Chemicals using P370+P378

42 chemicals in our database. Classification comes from each chemical's primary GHS source, so a supplier's SDS may differ.

P370+P378 frequently asked questions

What does P370+P378 mean?

P370+P378 says: "In case of fire: Use ... to extinguish". It is a response precautionary statement in the Response (P300 series). It combines P370, P378.

Which hazards call for P370+P378?

In the GHS data, P370+P378 is recommended for hazard statements H224, H225, H226, H227, H228, H242, H250, H260, H261, H271, H272, H282, H283.

What type of statement is P370+P378?

P370+P378 is in the Response (P300 series). P300 series: what to do after a spill, exposure or fire, including first-aid steps and when to call a poison center or doctor.

Precautionary statements are general recommendations. Follow the specific instructions on your product's label and safety data sheet.

https://pubchem.ncbi.nlm.nih.gov/ghs/ghscode_10.txt (UN GHS Revision 10, retrieved 2026-10-12)