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GHS precautionary statement

P370+P378: In case of fire: Use ... to extinguish

  • P370+P378
  • Response
  • Combined statement

P370+P378 says: “In case of fire: Use ... to extinguish”. It is a response statement that combines P370, P378. P300 series: what to do after a spill, exposure or fire, including first-aid steps and when to call a poison center or doctor.

The dots (...) mark a blank that the supplier fills in with specific information, such as the equipment, material or temperature that applies to the product.

About the response group

P300 series: what to do after a spill, exposure or fire, including first-aid steps and when to call a poison center or doctor. See all precautionary statements for the full list.

Component statements

A combined statement joins single statements that are printed as one sentence. This one is made of:

CodeStatement
P370In case of fire:
P378Use ... to extinguish.

Hazards that call for P370+P378

The GHS data recommends P370+P378 for these hazard statements.

CodeStatementHazard class and categorySignal word
H224Extremely flammable liquid and vapor
Flammable liquids — Category 1
Danger
H225Highly Flammable liquid and vapor
Flammable liquids — Category 2
Danger
H226Flammable liquid and vapor
Flammable liquids — Category 3
Warning
H227Combustible liquid
Flammable liquids — Category 4
Warning
H228Flammable solid
Flammable solids — Category 1
Flammable solids — Category 2
Danger
H242Heating may cause a fire
Self-reactive substances and mixtures; Organic peroxides — Type C, D
Self-reactive substances and mixtures; Organic peroxides — Type E, F
Danger
H250Catches fire spontaneously if exposed to air
Pyrophoric liquids — Category 1
Pyrophoric solids — Category 1
Danger
H260In contact with water releases flammable gases which may ignite spontaneously
Substances and mixtures which in contact with water, emit flammable gases — Category 1
Danger
H261In contact with water releases flammable gas
Substances and mixtures which in contact with water, emit flammable gases — Category 2
Substances and mixtures which in contact with water, emit flammable gases — Category 3
Danger
H271May cause fire or explosion; strong Oxidizer
Oxidizing liquids; Oxidizing solids — Category 1
Danger
H272May intensify fire; oxidizer
Oxidizing liquids; Oxidizing solids — Category 2
Oxidizing liquids; Oxidizing solids — Category 3
Danger
H282Extremely flammable chemical under pressure: may explode if heated
Chemicals under pressure — Category 1
Danger
H283Flammable chemical under pressure: may explode if heated
Chemicals under pressure — Category 2
Warning

Chemicals using P370+P378

63 chemicals in our database (showing the first 60 alphabetically). Classification comes from each chemical's primary GHS source, so a supplier's SDS may differ.

(+-)-2-Butanol
CAS 78-92-2 · Warning
1-Butanol
CAS 71-36-3 · Danger
1-Pentanol
CAS 71-41-0 · Warning
1-Propanol
CAS 71-23-8 · Danger
1,2,4-Trimethylbenzene
CAS 95-63-6 · Warning
1,3-Butanediol
CAS 107-88-0 · Warning
2-Heptanone
CAS 110-43-0 · Warning
2-Pentanol
CAS 6032-29-7 · Warning
2-Pentanone
CAS 107-87-9 · Danger
2,3-Butanediol
CAS 513-85-9 · Warning
5-Methyl-2-hexanone
CAS 110-12-3 · Warning
Acetic Acid
CAS 64-19-7 · Danger
Acetone
CAS 67-64-1 · Danger
Acetonitrile
CAS 75-05-8 · Danger
Acetylacetone
CAS 123-54-6 · Warning
Acrylic Acid
CAS 79-10-7 · Danger
Allyl Alcohol
CAS 107-18-6 · Danger
Alpha-Methylstyrene
CAS 98-83-9 · Warning
Benzene
CAS 71-43-2 · Danger
Butanedione
CAS 431-03-8 · Danger
Butyl Acetate
CAS 123-86-4 · Warning
Cadmium
CAS 7440-43-9 · Danger
Camphor
CAS 76-22-2 · Danger
Chromium Trioxide
CAS 1333-82-0 · Danger
Cumene
CAS 98-82-8 · Danger
Cyclohexane
CAS 110-82-7 · Danger
Cyclohexanone
CAS 108-94-1 · Warning
Cyclopentanone
CAS 120-92-3 · Warning
Decalin
CAS 91-17-8 · Danger
Diethyl Ether
CAS 60-29-7 · Danger
Epichlorohydrin
CAS 106-89-8 · Danger
Ethanol
CAS 64-17-5 · Danger
Ethyl Acetate
CAS 141-78-6 · Danger
Ethyl ketone
CAS 96-22-0 · Danger
Ethylbenzene
CAS 100-41-4 · Danger
Heptane
CAS 142-82-5 · Danger
Hexane
CAS 110-54-3 · Danger
Hydrogen Peroxide
CAS 7722-84-1 · Danger
Isoamyl Alcohol
CAS 123-51-3 · Danger
Isobutanol
CAS 78-83-1 · Danger
Isopropanol
CAS 67-63-0 · Danger
M-Xylene
CAS 108-38-3 · Warning
Mesityl oxide
CAS 141-79-7 · Warning
Mesitylene
CAS 108-67-8 · Warning
Methanol
CAS 67-56-1 · Danger
Methyl Ethyl Ketone
CAS 78-93-3 · Danger
Methyl Isobutyl Ketone
CAS 108-10-1 · Danger
Methyl Methacrylate
CAS 80-62-6 · Danger
Nitric Acid
CAS 7697-37-2 · Danger
O-Xylene
CAS 95-47-6 · Warning
P-Cymene
CAS 99-87-6 · Danger
P-Xylene
CAS 106-42-3 · Warning
Potassium Dichromate
CAS 7778-50-9 · Danger
Potassium Permanganate
CAS 7722-64-7 · Danger
Propargyl alcohol
CAS 107-19-7 · Danger
Propylene Oxide
CAS 75-56-9 · Danger
Silver Nitrate
CAS 7761-88-8 · Danger
Sodium Lauryl Sulfate
CAS 151-21-3 · Danger
Sodium Nitrite
CAS 7632-00-0 · Danger
Styrene
CAS 100-42-5 · Danger

P370+P378 frequently asked questions

What does P370+P378 mean?

P370+P378 says: "In case of fire: Use ... to extinguish". It is a response precautionary statement in the Response (P300 series). It combines P370, P378.

Which hazards call for P370+P378?

In the GHS data, P370+P378 is recommended for hazard statements H224, H225, H226, H227, H228, H242, H250, H260, H261, H271, H272, H282, H283.

What type of statement is P370+P378?

P370+P378 is in the Response (P300 series). P300 series: what to do after a spill, exposure or fire, including first-aid steps and when to call a poison center or doctor.

Precautionary statements are general recommendations. Follow the specific instructions on your product's label and safety data sheet.

https://pubchem.ncbi.nlm.nih.gov/ghs/ghscode_10.txt (UN GHS Revision 10, retrieved 2026-10-12)