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GHS precautionary statement

P321: Specific treatment (see ... on this label)

  • P321
  • Response

P321 says: “Specific treatment (see ... on this label)”. It is a response statement. P300 series: what to do after a spill, exposure or fire, including first-aid steps and when to call a poison center or doctor.

The dots (...) mark a blank that the supplier fills in with specific information, such as the equipment, material or temperature that applies to the product.

About the response group

P300 series: what to do after a spill, exposure or fire, including first-aid steps and when to call a poison center or doctor. See all precautionary statements for the full list.

Hazards that call for P321

The GHS data recommends P321 for these hazard statements.

CodeStatementHazard class and categorySignal word
H300Fatal if swallowed
Acute toxicity, oral — Category 1, 2
Danger
H301Toxic if swallowed
Acute toxicity, oral — Category 3
Danger
H310Fatal in contact with skin
Acute toxicity, dermal — Category 1, 2
Danger
H311Toxic in contact with skin
Acute toxicity, dermal — Category 3
Danger
H312Harmful in contact with skin
Acute toxicity, dermal — Category 4
Warning
H314Causes severe skin burns and eye damage
Skin corrosion/irritation — Category 1, 1A, 1B, 1C
Danger
H315Causes skin irritation
Skin corrosion/irritation — Category 2
Warning
H317May cause an allergic skin reaction
Sensitization, Skin — Category 1, 1A, 1B
Warning
H331Toxic if inhaled
Acute toxicity, inhalation — Category 3
Danger
H370Causes damage to organs
Specific target organ toxicity, single exposure — Category 1
Danger

Chemicals using P321

69 chemicals in our database (showing the first 60 alphabetically). Classification comes from each chemical's primary GHS source, so a supplier's SDS may differ.

1-Butanol
CAS 71-36-3 · Danger
1-Decanol
CAS 112-30-1 · Warning
1-Nonanol
CAS 143-08-8 · Warning
1-Octanol
CAS 111-87-5 · Warning
1-Pentanol
CAS 71-41-0 · Warning
1-Tetradecanol
CAS 112-72-1 · Warning
1,3-Propanediol
CAS 504-63-2 · Warning
2-Butoxyethanol
CAS 111-76-2 · Danger
2-Ethylhexanol
CAS 104-76-7 · Warning
2-Octanol
CAS 123-96-6 · Danger
Acetic Acid
CAS 64-19-7 · Danger
Acetonitrile
CAS 75-05-8 · Danger
Acrylamide
CAS 79-06-1 · Danger
Acrylic Acid
CAS 79-10-7 · Danger
Allyl Alcohol
CAS 107-18-6 · Danger
Ammonia
CAS 7664-41-7 · Danger
Ammonium Hydroxide
CAS 1336-21-6 · Danger
Aniline
CAS 62-53-3 · Danger
Arsenic
CAS 7440-38-2 · Danger
Benzene
CAS 71-43-2 · Danger
Benzyl Alcohol
CAS 100-51-6 · Warning
Bisphenol A
CAS 80-05-7 · Danger
Calcium Hydroxide
CAS 1305-62-0 · Danger
Calcium Oxide
CAS 1305-78-8 · Danger
Carbon Monoxide
CAS 630-08-0 · Danger
Chlorine
CAS 7782-50-5 · Danger
Chloroform
CAS 67-66-3 · Danger
Chromium Trioxide
CAS 1333-82-0 · Danger
Copper Sulfate
CAS 7758-98-7 · Warning
Cyclohexane
CAS 110-82-7 · Danger
Cyclohexanol
CAS 108-93-0 · Warning
Dimethyl Sulfoxide
CAS 67-68-5 · Warning
Dimethylformamide
CAS 68-12-2 · Danger
Diphenylmethane diisocyanate
CAS 101-68-8 · Danger
Dipropylene Glycol
CAS 25265-71-8 · Danger
Epichlorohydrin
CAS 106-89-8 · Danger
Ethanolamine
CAS 141-43-5 · Danger
Ethylene Oxide
CAS 75-21-8 · Danger
Formaldehyde
CAS 50-00-0 · Danger
Furfuryl Alcohol
CAS 98-00-0 · Danger
Heptane
CAS 142-82-5 · Danger
Hexane
CAS 110-54-3 · Danger
Hydrochloric Acid
CAS 7647-01-0 · Danger
Hydrofluoric Acid
CAS 7664-39-3 · Danger
Hydrogen Peroxide
CAS 7722-84-1 · Danger
Isoamyl Alcohol
CAS 123-51-3 · Danger
Isobutanol
CAS 78-83-1 · Danger
Methanol
CAS 67-56-1 · Danger
Methyl Methacrylate
CAS 80-62-6 · Danger
Neopentyl glycol
CAS 126-30-7 · Danger
Nitric Acid
CAS 7697-37-2 · Danger
Phenol
CAS 108-95-2 · Danger
Phosphoric Acid
CAS 7664-38-2 · Danger
Potassium Dichromate
CAS 7778-50-9 · Danger
Potassium Hydroxide
CAS 1310-58-3 · Danger
Propargyl alcohol
CAS 107-19-7 · Danger
Propylene Glycol
CAS 57-55-6 · Danger
Propylene Oxide
CAS 75-56-9 · Danger
Silver Nitrate
CAS 7761-88-8 · Danger
Sodium Cyanide
CAS 143-33-9 · Danger

P321 frequently asked questions

What does P321 mean?

P321 says: "Specific treatment (see ... on this label)". It is a response precautionary statement in the Response (P300 series).

Which hazards call for P321?

In the GHS data, P321 is recommended for hazard statements H300, H301, H310, H311, H312, H314, H315, H317, H331, H370.

What type of statement is P321?

P321 is in the Response (P300 series). P300 series: what to do after a spill, exposure or fire, including first-aid steps and when to call a poison center or doctor.

Precautionary statements are general recommendations. Follow the specific instructions on your product's label and safety data sheet.

https://pubchem.ncbi.nlm.nih.gov/ghs/ghscode_10.txt (UN GHS Revision 10, retrieved 2026-10-12)