Ammonia

1Identification

Name

Ammonia

IUPAC name

azane

CAS number

7664-41-7

EC number

231-635-3

Molecular formula

H3N

Molecular weight

17.031 g/mol

InChIKey

QGZKDVFQNNGYKY-UHFFFAOYSA-N

SMILES

N

PubChem CID

222

Synonyms

ammonia, azane, Ammonia gas, Nitro-sil, Ammonia anhydrous, Ammonia, anhydrous, Anhydrous ammonia, Ammoniak, Liquid Ammonia, AM-Fol, ammoniac, Aqueous ammonia, Refrigerent R717, amoniaco

Recommended uses

• CIR ingredient: Ammonia
  Cosmetic Ingredient Review (CIR)
• About 80% is used in fertilizers; it also is used as a refrigerant gas, and in the manufacture of plastics, explosives, pesticides, detergents, and other chemicals. Small amounts of ammonia occur naturally from decomposition of organic matter. [ATSDR Medical Management] Also used in illicit methamphetamine labs; Anhydrous ammonia is the most commonly reported agent in accidental spill or release incidents. [PMID 19225422]
  Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
• Molding and Core Making [Category: Foundry] Heat Treating [Category: Heat or Machine] Electroplating [Category: Plate] Petroleum Production and Refining [Category: Industry] Semiconductor Manufacturing [Category: Industry] Pulp and Paper Processing [Category: Industry] Sewer and Wastewater Treatment [Category: Industry] Firefighting [Category: Other] Leather Tanning and Processing [Category: Industry] Photographic Processing [Category: Other] Fur Dressing and Dyeing [Category: Industry] Burning Synthetic Polymers [Category: Burn] Farming (Respiratory Hazards) [Category: Industry]
  Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
• Soil amendments (fertilizers) Not Known or Reasonably Ascertainable Ion exchange agent Catalyst Stabilizing agent Refrigerants Reducing agent Cleaning agent Flame retardant Oxidizing agent Intermediate Processing aids, specific to petroleum production Drier Other Binder Energy Releasers (explosives, motive propellant) pH regulating agent Fuel agents Chemical reaction regulator Processing aids, not otherwise listed Tanning agents not otherwise specified Processing aids not otherwise specified
  EPA Chemical Data Reporting (CDR)
• Semiconductor and photovoltaic agent Processing aids not otherwise specified pH regulating agent Fuel agents Chemical reaction regulator Other Intermediate Soil amendments (fertilizers) Not Known or Reasonably Ascertainable Ion exchange agent Stabilizing agent Reducing agent
  EPA Chemical Data Reporting (CDR)

Use categories: Cosmetics -> Buffering

Description

• Ammonia occurs naturally and is produced by human activity. It is an important source of nitrogen which is needed by plants and animals. Bacteria found in the intestines can produce ammonia. Ammonia is a colorless gas with a very distinct odor. This odor is familiar to many people because ammonia is used in smelling salts, many household and industrial cleaners, and window-cleaning products. Ammonia gas can be dissolved in water. This kind of ammonia is called liquid ammonia or aqueous ammonia. Once exposed to open air, liquid ammonia quickly turns into a gas. Ammonia is applied directly into soil on farm fields, and is used to make fertilizers for farm crops, lawns, and plants.
  Agency for Toxic Substances and Disease Registry (ATSDR)
• Ammonia solutions (containing more than 35% but not more than 50% ammonia) appears as a clear colorless liquid consisting of ammonia dissolved in water. Corrosive to tissue and metals. Although ammonia is lighter than air, the vapors from a leak will initially hug the ground. Long term exposure to low concentrations or short term exposure to high concentrations may result in adverse health conditions from inhalation. Prolonged exposure of containers to fire or heat may result in their violent rupturing and rocketing.
  CAMEO Chemicals
• Ammonia, anhydrous appears as a clear colorless gas with a strong odor. Shipped as a liquid under its own vapor pressure. Density (liquid) 6 lb / gal. Contact with the unconfined liquid can cause frostbite. Gas generally regarded as nonflammable but does burn within certain vapor concentration limits and with strong ignition. Fire hazard increases in the presence of oil or other combustible materials. Although gas is lighter than air, vapors from a leak initially hug the ground. Prolonged exposure of containers to fire or heat may cause violent rupturing and rocketing.
  CAMEO Chemicals

2Hazard identification

Signal word

Danger

Pictograms

GHS04, GHS05, GHS06, GHS09

Classification source

Regulation (EC) No 1272/2008 of the European Parliament and of the Council

Precautionary statements

Other reported classifications

8 classification records exist across sources. Differences usually reflect purity, physical form or impurities.

NFPA 704 rating

• 3 - Materials that, under emergency conditions, can cause serious or permanent injury.
  Hazardous Substances Data Bank (HSDB)
• 1 - Materials that must be preheated before ignition can occur. Materials require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur.
  Hazardous Substances Data Bank (HSDB)
• 0 - Materials that in themselves are normally stable, even under fire conditions.
  Hazardous Substances Data Bank (HSDB)

Health hazards

• Excerpt from ERG Guide 125 [Gases - Toxic and/or Corrosive]: TOXIC and/or CORROSIVE; may be fatal if inhaled, ingested or absorbed through skin. Vapors are extremely irritating and corrosive. Contact with gas or liquefied gas may cause burns, severe injury and/or frostbite. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may cause environmental contamination. (ERG, 2024)
  CAMEO Chemicals
• Vapors cause irritation of eyes and respiratory tract. Liquid will burn skin and eyes. Poisonous; may be fatal if inhaled. Contact may cause burns to skin and eyes. Contact with liquid may cause frostbite. (EPA, 1998)
  CAMEO Chemicals
• Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: TOXIC and/or CORROSIVE; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause environmental contamination. (ERG, 2024)
  CAMEO Chemicals

Fire hazards

• Excerpt from ERG Guide 125 [Gases - Toxic and/or Corrosive]: Some may burn but none ignite readily. Vapors from liquefied gas are initially heavier than air and spread along ground. Some of these materials may react violently with water. Cylinders exposed to fire may vent and release toxic and/or corrosive gas through pressure relief devices. Containers may explode when heated. Ruptured cylinders may rocket. For UN1005: Anhydrous ammonia, at high concentrations in confined spaces, presents a flammability risk if a source of ignition is introduced. (ERG, 2024)
  CAMEO Chemicals
• Mixing of ammonia with several chemicals can cause severe fire hazards and/or explosions. Ammonia in container may explode in heat of fire. Incompatible with many materials including silver and gold salts, halogens, alkali metals, nitrogen trichloride, potassium chlorate, chromyl chloride, oxygen halides, acid vapors, azides, ethylene oxide, picric acid and many other chemicals. Mixing with other chemicals and water. Hazardous polymerization may not occur. (EPA, 1998)
  CAMEO Chemicals
• Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Corrosives in contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. For electric vehicles or equipment, ERG Guide 147 (lithium ion or sodium ion batteries) or ERG Guide 138 (sodium batteries) should also be consulted. (ERG, 2024)
  CAMEO Chemicals

Hazards summary

• Ammonia occurs naturally and is produced by human activity. It is an important source of nitrogen which is needed by plants and animals. Bacteria found in the intestines can produce ammonia. Ammonia is a colorless gas with a very distinct odor. This odor is familiar to many people because ammonia is used in smelling salts, many household and industrial cleaners, and window-cleaning products. Ammonia gas can be dissolved in water. This kind of ammonia is called liquid ammonia or aqueous ammonia. Once exposed to open air, liquid ammonia quickly turns into a gas. Ammonia is applied directly into soil on farm fields, and is used to make fertilizers for farm crops, lawns, and plants.
  Agency for Toxic Substances and Disease Registry (ATSDR)
• Liquid causes first degree burns on short exposure; [CHRIS] Ammonia gas and liquid are corrosive to skin. [Quick CPC] Ingestion of industrial strength ammonia (27-30%) causes esophageal burns with liquefaction necrosis and the possibility of later perforation and stricture formation. Inhalation of concentrated ammonia can cause acute lung injury. Household ammonia (5-10%) is not likely to cause serious burns. [HSDB] The concentration of aqueous ammonia solutions for household use is typically 5% to 10% (weight:volume), but solutions for commercial use may be 25% (weight:volume) or more and are corrosive. [ATSDR Medical Management] Listed as one of major irritant airborne toxicants;
  Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

3Composition / information on ingredients

This page describes the pure substance. Commercial products may be solutions or mixtures. Check Section 3 of your supplier's SDS for concentrations and other ingredients.

4First-aid measures

• Excerpt from ERG Guide 125 [Gases - Toxic and/or Corrosive]: Refer to the "General First Aid" section. Specific First Aid: In case of contact with liquefied gas, only medical personnel should attempt thawing frosted parts. In case of skin contact with hydrogen fluoride, anhydrous (UN1052), if calcium gluconate gel is available, rinse 5 minutes, then apply gel. Otherwise, continue rinsing until medical treatment is available. (ERG, 2024)
  CAMEO Chemicals
• Warning: Ammonia is extremely corrosive to the skin, eyes, and mucous membranes. Contact with the liquified gas may cause frostbite. Caution is advised. Signs and Symptoms of Acute Ammonia Exposure: Inhalation of ammonia may cause irritation and burns of the respiratory tract, laryngitis, dyspnea (shortness of breath), stridor (high-pitched respirations), and chest pain. Pulmonary edema and pneumonia may also result from inhalation. A pink frothy sputum, convulsions, and coma are often seen following exposure to high concentrations. When ammonia is ingested, nausea and vomiting may result; oral, esophageal, and stomach burns are common.
  CAMEO Chemicals
• Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: Refer to the "General First Aid" section. Specific First Aid: For corrosives, in case of contact, immediately flush skin or eyes with running water for at least 30 minutes. Additional flushing may be required. (ERG, 2024)
  CAMEO Chemicals
• General First Aid: · Call 911 or emergency medical service. · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination. · Move victim to fresh air if it can be done safely. · Administer oxygen if breathing is difficult. · If victim is not breathing: -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance. -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).
  Emergency Response Guidebook (ERG)

Symptoms of exposure

• Burning sensation. Cough. Laboured breathing. Shortness of breath. Sore throat.
  ILO-WHO International Chemical Safety Cards (ICSCs)
• Redness. Pain. Blisters. Skin burns. ON CONTACT WITH LIQUID: FROSTBITE.
  ILO-WHO International Chemical Safety Cards (ICSCs)
• Redness. Pain. Severe burns. ON CONTACT WITH LIQUID: FROSTBITE.
  ILO-WHO International Chemical Safety Cards (ICSCs)

5Fire-fighting measures

• Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
  Hazardous Substances Data Bank (HSDB)
• Advice for firefighters: Wear self-contained breathing apparatus for firefighting if necessary.
  Hazardous Substances Data Bank (HSDB)
• Use water spray to cool unopened containers.
  Hazardous Substances Data Bank (HSDB)

Hazardous combustion products

• Fire will produce irritating, corrosive, and/or toxic gases.
  Hazardous Substances Data Bank (HSDB)

6Accidental release measures

Isolation and evacuation

• Excerpt from ERG Guide 125 [Gases - Toxic and/or Corrosive]: IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area for at least 100 meters (330 feet) in all directions. SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary. FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 1600 meters (1 mile) in all directions; also, consider initial evacuation for 1600 meters (1 mile) in all directions. (ERG, 2024)
  CAMEO Chemicals
• Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary. FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)
  CAMEO Chemicals

Spill cleanup

• Evacuate danger area! Consult an expert! Personal protection: gas-tight chemical protection suit including self-contained breathing apparatus. Ventilation. Shut off cylinder if possible. Isolate the area until the gas has dispersed. Remove gas with fine water spray. NEVER direct water jet on liquid.
  ILO-WHO International Chemical Safety Cards (ICSCs)
• ACCIDENTAL RELEASE MEASURES: Personal precautions, protective equipment and emergency procedures: Wear respiratory protection. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapors accumulating to form explosive concentrations. Vapors can accumulate in low areas. Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
  Hazardous Substances Data Bank (HSDB)
• SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal.
  Hazardous Substances Data Bank (HSDB)
• Wear a self-contained breathing apparatus, eye protection, laboratory coat, and nitrile rubber gloves (and rubber boots or overshoes if spillage is large). Cover the spill with a 1:1:1 mixture by weight of sodium carbonate or calcium carbonate, clay cat litter (bentonite), and sand. Scoop the mixture into a plastic pail and, in the fume hood, add to a pail of cold water. Neutralize the mixture with 5% hydrochloric acid, let stand overnight, and then pour liquid into the drain. Dispose of any solid with normal refuse. Wash area of the spill with plenty of water.
  Hazardous Substances Data Bank (HSDB)

7Handling and storage

• Fireproof. Separated from oxidants, acids and halogens. Cool. Keep in a well-ventilated room.
  ILO-WHO International Chemical Safety Cards (ICSCs)
• Keep container tightly closed in a dry and well-ventilated place. Contents under pressure. Storage class (TRGS 510): Gases
  Hazardous Substances Data Bank (HSDB)
• Before entering confined space where this chemical may be present, check to make sure that an explosive concentration does not exist. Protect against physical damage. Outside or detached storage is preferred. Inside storage should be in a cool, well-ventilated, noncombustible location, preferably with automatic monitoring systems, away from all possible sources of ignition. Separate from other chemicals, particularly oxidizing gases, chlorine, bromine, iodine, and acids.
  Hazardous Substances Data Bank (HSDB)
• SRP: Operations involving entry into tanks or closed vessels, and emergency situations, require consideration of potentially oxygen deficient, or "immediately dangerous to life and health" IDLH environments. This may necessitate use of a self-contained breathing apparatus (SCBA), or a positive pressure supplied air respirator.
  Hazardous Substances Data Bank (HSDB)

8Exposure controls / personal protection

Personal protective equipment

• Excerpt from ERG Guide 125 [Gases - Toxic and/or Corrosive]: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE. Structural firefighters' protective clothing provides thermal protection but only limited chemical protection. (ERG, 2024)
  CAMEO Chemicals
• For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)
  CAMEO Chemicals
• Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE. Structural firefighters' protective clothing provides thermal protection but only limited chemical protection. (ERG, 2024)
  CAMEO Chemicals
• Eye/face protection: Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
  Hazardous Substances Data Bank (HSDB)

Respirator recommendations

• NIOSH Up to 250 ppm: (APF = 10) Any chemical cartridge respirator with cartridge(s) providing protection against the compound of concern* (APF = 10) Any supplied-air respirator* Up to 300 ppm: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode* (APF = 25) Any powered, air-purifying respirator with cartridge(s) providing protection against the compound of concern* (APF = 50) Any chemical cartridge respirator with a full facepiece and cartridge(s) providing protection against the compound of concern (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted canister providing protection against the compound of concern (AP…
  The National Institute for Occupational Safety and Health (NIOSH)

9Physical and chemical properties

10Stability and reactivity

Reactivity

• Ammonia solutions react exothermically with acids to produce water and ammonium salts, Heating or treating with strong bases also causes evolution of gaseous ammonia. Ammonia can burn or explode if exposed to an intense source of ignition but can generally be treated as nonflammable. Readily combines with silver oxide, silver chloride, silver nitrate, silver azide or mercury to form explosive compounds. Forms explosive ammonium chlorate on contact with chlorates [Kirk-Othmer, 3rd ed., Vol. 2, 1978, p. 470]. Reacts violently or produces explosive products with fluorine, chlorine, bromine and iodine and bromine pentafluoride and chlorine trifluoride.
  CAMEO Chemicals
• AMMONIA is a base. Reacts exothermically with all acids. Violent reactions are possible. Readily combines with silver oxide or mercury to form compounds that explode on contact with halogens. When in contact with chlorates it forms explosive ammonium chlorate [Kirk-Othmer, 3rd ed., Vol. 2, 1978, p. 470]. Reacts violently or produces explosive products with fluorine, chlorine, bromine and iodine and some of the interhalogen compounds (bromine pentafluoride, chlorine trifluoride). Mixing of bleaching powder (hypochlorite solution) with ammonia solutions produces toxic/explosive ammonia trichloride vapors.
  CAMEO Chemicals
• Soluble in water with evolution of heat. The amount of heat generated may be large.
  CAMEO Chemicals

Incompatible materials and hazardous reactions

• Incompatible materials: Oxidizing agents, iron, zinc, copper, silver/silver oxides, cadmium/cadmium oxides, alcohols, acids, halogens, aldehydes.
  Hazardous Substances Data Bank (HSDB)
• Shock-sensitive compounds may be formed with gold, halogens, mercury, mercury oxide, and silver oxide.
  Hazardous Substances Data Bank (HSDB)
• Attacks some coatings, plastics, rubber, copper, brass, bronze. aluminum, steel, tin, zinc, and their alloys.
  Hazardous Substances Data Bank (HSDB)

Chemical stability

• Stable under recommended storage conditions.
  Hazardous Substances Data Bank (HSDB)

11Toxicological information

Target organs

• Dermal (Skin), Neurological (Nervous System), Ocular (Eyes), Respiratory (From the Nose to the Lungs)
  Agency for Toxic Substances and Disease Registry (ATSDR)
• Respiratory
  EPA Integrated Risk Information System (IRIS)

Short-term exposure effects

• Rapid evaporation of the liquid may cause frostbite. The substance is corrosive to the eyes, skin and respiratory tract. Exposure could cause asphyxiation due to swelling in the throat. Inhalation may cause lung oedema, but only after initial corrosive effects on eyes and/or airways have become manifest.
  ILO-WHO International Chemical Safety Cards (ICSCs)

Long-term exposure effects

• Repeated or chronic inhalation of the vapour may cause chronic inflammation of the upper respiratory tract. Lungs may be affected by repeated or prolongated exposure. This may result in chronic obstructive pulmonary disorders (COPD).
  ILO-WHO International Chemical Safety Cards (ICSCs)

12Ecological information

Not available in the public sources we compile. Check Section 12 of the supplier's SDS.

13Disposal considerations

• SRP: Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in air, soil or water; effects on animal, aquatic and plant life; and conformance with environmental and public health regulations. If it is possible or reasonable use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination.
  Hazardous Substances Data Bank (HSDB)
• SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal.
  Hazardous Substances Data Bank (HSDB)
• Product: Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting as this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Contaminated packaging: Dispose of as unused product.
  Hazardous Substances Data Bank (HSDB)

14Transport information

UN numbers: UN 1005, UN 2073, UN 2672, UN 3318

Shipping name

• UN 1005; Ammonia, anhydrous
  Hazardous Substances Data Bank (HSDB)
• UN 2073; Ammonia solutions, relative density less than 0.880 at 15 °C in water, with more than 35% but not more than 50% ammonia
  Hazardous Substances Data Bank (HSDB)

DOT hazard class

• Ammonia, anhydrous (I)
  US Code of Federal Regulations, Hazardous Materials, 49 CFR Part 172
• Marine pollutant
  US Code of Federal Regulations, Hazardous Materials, 49 CFR Part 172
• Ammonia, anhydrous
  US Code of Federal Regulations, Hazardous Materials, 49 CFR Part 172

DOT label

• Non-Flammable Gas
  CAMEO Chemicals
• Non-Flammable Gas (domestic) Inhalation Hazard (Special Provision 13) (domestic) Poison Gas (international) Corrosive (international)
  CAMEO Chemicals

UN classification

• UN Hazard Class: 2.3; UN Subsidiary Risks: 8
  ILO-WHO International Chemical Safety Cards (ICSCs)

Emergency Response Guidebook

• 1005 125
  Emergency Response Guidebook (ERG)
• 1005 125(anhydrous)
  The National Institute for Occupational Safety and Health (NIOSH)

How DOT hazard classes work →

15Regulatory information

• New Active Ingredients ... includes chemicals not previously registered as pesticides, as well as pesticide active ingredients initially registered after November 1, 1984 and that currently have active product registrations. By law, these pesticides must meet new safety standards, such as those described in the Food Quality Protection Act of 1996 and, if new safety standards are met, will be reviewed again on a 15-year cycle. Ammonia is designated by EPA as a New Pesticide Active Ingredient. Active Ingredient Number: 005302; Type of Pesticide: insecticide; Use Site: non-food use; Year: 1994.
  Hazardous Substances Data Bank (HSDB)
• Ammonia is designated as a hazardous substance under section 311(b)(2)(A) of the Federal Water Pollution Control Act and further regulated by the Clean Water Act Amendments of 1977 and 1978. These regulations apply to discharges of this substance. This designation includes any isomers and hydrates, as well as any solutions and mixtures containing this substance.
  Hazardous Substances Data Bank (HSDB)
• Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 100 lb or 45.4 kg. The toll free number of the NRC is (800) 424-8802. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b).
  Hazardous Substances Data Bank (HSDB)
• Ammonia is an indirect food additive for use only as a component of adhesives.
  Hazardous Substances Data Bank (HSDB)

Overview of SDS regulations (OSHA HazCom, WHMIS, REACH/CLP) →

16Other information

Compiled from PubChem CID 222 and the sources it aggregates (attributed inline). Data retrieved 2026-10-12. This summary describes the pure substance and is not a supplier SDS.