GHS hazard statement
H335: May cause respiratory irritation
- H335
- Health hazards
- Warning
H335 means “May cause respiratory irritation”. It is a GHS hazard statement for Specific target organ toxicity, single exposure; Respiratory tract irritation (Category 3), shown with GHS07 under the signal word “Warning”.
Hazard class and category
| Hazard class | Category | Pictogram | Signal word | UN transport class |
|---|---|---|---|---|
| Specific target organ toxicity, single exposure; Respiratory tract irritation | Category 3 |  | Warning | — |
What H335 means
Specific target organ toxicity after single exposure covers non-lethal effects on a specific organ system from one exposure. The GHS includes respiratory tract irritation and narcotic effects (drowsiness or dizziness) in this class.
One exposure can irritate the airways or cause drowsiness, dizziness or other effects on a target organ.
What to do
Avoid breathing dust, fumes, vapor or mist, use only outdoors or in a well-ventilated area, and move a person who is affected to fresh air. Call a poison center or doctor if the person feels unwell.
This is general guidance for the hazard class. The safety data sheet for your product always takes precedence.
Precautionary statements for H335
The GHS lists these precautionary statements for this hazard. Which ones appear on a label depends on the supplier's classification.
| Code | Statement |
|---|---|
| P261 | Avoid breathing dust/fume/gas/mist/vapors/spray. |
| P271 | Use only outdoors or in a well-ventilated area. |
| P304+P340 | IF INHALED: Remove person to fresh air and keep comfortable for breathing. |
| P319 | Get medical help if you feel unwell. |
| P403+P233 | Store in a well-ventilated place. Keep container tightly closed. |
| P405 | Store locked up. |
| P501 | Dispose of contents/container to ... |
Chemicals carrying H335
25 chemicals in our database. Classification comes from each chemical's primary GHS source, so a supplier's SDS may differ.
H335 frequently asked questions
What does H335 mean?
H335 means "May cause respiratory irritation". It is a GHS hazard statement in the health hazards group, covering Specific target organ toxicity, single exposure; Respiratory tract irritation (Category 3).
Which pictogram goes with H335?
H335 is shown with GHS07 (Exclamation Mark).
What signal word goes with H335?
The signal word for H335 is "Warning".
Which precautionary statements go with H335?
The GHS data lists 7 precautionary statements for H335, including P261, P271, P304+P340, P319, P403+P233. They cover prevention, response, storage and disposal. The full list is on this page.
Hazard statements describe the hazard of a classified substance or mixture. The classification of a specific product can differ, so use the supplier's SDS.
https://pubchem.ncbi.nlm.nih.gov/ghs/ghscode_10.txt (UN GHS Revision 10, retrieved 2026-10-12)