GHS hazard class · Health hazards
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity after single exposure covers non-lethal effects on a specific organ system from one exposure. The GHS includes respiratory tract irritation and narcotic effects (drowsiness or dizziness) in this class.
What it means
One exposure can irritate the airways or cause drowsiness, dizziness or other effects on a target organ.
What to do
Avoid breathing dust, fumes, vapor or mist, use only outdoors or in a well-ventilated area, and move a person who is affected to fresh air. Call a poison center or doctor if the person feels unwell.
This is general guidance for the class. Your product's safety data sheet takes precedence.
Categories and hazard statements
| Code | Category | Statement | Pictogram | Signal word |
|---|---|---|---|---|
| H335 | Category 3 | May cause respiratory irritation | GHS07 | Warning |
Chemicals with specific target organ toxicity, single exposure; respiratory tract irritation hazard codes
Chemicals in our database whose primary classification includes any current Specific target organ toxicity, single exposure; Respiratory tract irritation code (H335).
25 chemicals in our database. Classification comes from each chemical's primary GHS source, so a supplier's SDS may differ.
Specific target organ toxicity, single exposure; Respiratory tract irritation: frequently asked questions
What is the GHS hazard class "Specific target organ toxicity, single exposure; Respiratory tract irritation"?
Specific target organ toxicity after single exposure covers non-lethal effects on a specific organ system from one exposure. The GHS includes respiratory tract irritation and narcotic effects (drowsiness or dizziness) in this class.
Which hazard statements belong to Specific target organ toxicity, single exposure; Respiratory tract irritation?
The current hazard statements for this class are H335.
Which pictograms and signal words are used for Specific target organ toxicity, single exposure; Respiratory tract irritation?
Pictograms: GHS07 (Exclamation Mark). Signal word: Warning, depending on the category.
What should I do when working with a specific target organ toxicity, single exposure; respiratory tract irritation hazard?
Avoid breathing dust, fumes, vapor or mist, use only outdoors or in a well-ventilated area, and move a person who is affected to fresh air. Call a poison center or doctor if the person feels unwell.
https://pubchem.ncbi.nlm.nih.gov/ghs/ghscode_10.txt (UN GHS Revision 10, retrieved 2026-10-12)