GHS hazard class · Health hazards
Specific target organ toxicity, repeated exposure
Specific target organ toxicity after repeated exposure covers significant organ damage that develops from repeated or prolonged exposure to a substance, by any route relevant to people.
What it means
Damage to a named organ such as the liver, kidneys, nervous system or lungs can develop over time even if each exposure seems small.
What to do
Limit and control exposure, do not breathe dust, vapor or mist, wear the protective equipment the SDS calls for, follow workplace exposure limits and any health surveillance program, and get medical advice if you feel unwell.
This is general guidance for the class. Your product's safety data sheet takes precedence.
Categories and hazard statements
Chemicals with specific target organ toxicity, repeated exposure hazard codes
Chemicals in our database whose primary classification includes any current Specific target organ toxicity, repeated exposure code (H372, H373).
18 chemicals in our database. Classification comes from each chemical's primary GHS source, so a supplier's SDS may differ.
Specific target organ toxicity, repeated exposure: frequently asked questions
What is the GHS hazard class "Specific target organ toxicity, repeated exposure"?
Specific target organ toxicity after repeated exposure covers significant organ damage that develops from repeated or prolonged exposure to a substance, by any route relevant to people.
Which hazard statements belong to Specific target organ toxicity, repeated exposure?
The current hazard statements for this class are H372, H373.
Which pictograms and signal words are used for Specific target organ toxicity, repeated exposure?
Pictograms: GHS08 (Health Hazard). Signal words: Danger or Warning, depending on the category.
What should I do when working with a specific target organ toxicity, repeated exposure hazard?
Limit and control exposure, do not breathe dust, vapor or mist, wear the protective equipment the SDS calls for, follow workplace exposure limits and any health surveillance program, and get medical advice if you feel unwell.
https://pubchem.ncbi.nlm.nih.gov/ghs/ghscode_10.txt (UN GHS Revision 10, retrieved 2026-10-12)