GHS hazard statement
H373: May causes damage to organs through prolonged or repeated exposure
- H373
- Health hazards
- Warning
H373 means “May causes damage to organs through prolonged or repeated exposure”. It is a GHS hazard statement for Specific target organ toxicity, repeated exposure (Category 2), shown with GHS08 under the signal word “Warning”.
Hazard class and category
| Hazard class | Category | Pictogram | Signal word | UN transport class |
|---|---|---|---|---|
| Specific target organ toxicity, repeated exposure | Category 2 |  | Warning | — |
What H373 means
Specific target organ toxicity after repeated exposure covers significant organ damage that develops from repeated or prolonged exposure to a substance, by any route relevant to people.
Damage to a named organ such as the liver, kidneys, nervous system or lungs can develop over time even if each exposure seems small.
What to do
Limit and control exposure, do not breathe dust, vapor or mist, wear the protective equipment the SDS calls for, follow workplace exposure limits and any health surveillance program, and get medical advice if you feel unwell.
This is general guidance for the hazard class. The safety data sheet for your product always takes precedence.
Precautionary statements for H373
The GHS lists these precautionary statements for this hazard. Which ones appear on a label depends on the supplier's classification.
Chemicals carrying H373
4 chemicals in our database. Classification comes from each chemical's primary GHS source, so a supplier's SDS may differ.
H373 frequently asked questions
What does H373 mean?
H373 means "May causes damage to organs through prolonged or repeated exposure". It is a GHS hazard statement in the health hazards group, covering Specific target organ toxicity, repeated exposure (Category 2).
Which pictogram goes with H373?
H373 is shown with GHS08 (Health Hazard).
What signal word goes with H373?
The signal word for H373 is "Warning".
Which precautionary statements go with H373?
The GHS data lists 3 precautionary statements for H373, including P260, P319, P501. They cover prevention, response, storage and disposal. The full list is on this page.
Hazard statements describe the hazard of a classified substance or mixture. The classification of a specific product can differ, so use the supplier's SDS.
https://pubchem.ncbi.nlm.nih.gov/ghs/ghscode_10.txt (UN GHS Revision 10, retrieved 2026-10-12)