GHS hazard class · Health hazards
Reproductive toxicity
Reproductive toxicity covers adverse effects on sexual function and fertility in adults, and on the development of offspring. Substances are categorized by how strong the evidence is that they harm fertility or the unborn child.
What it means
Exposure may damage fertility or harm the unborn child. Effects depend on dose and timing.
What to do
Obtain special instructions before use, do not handle until all safety precautions are understood, use the protective equipment the SDS names, and talk to your employer or occupational health professional before working with the material if you are pregnant or planning a pregnancy.
This is general guidance for the class. Your product's safety data sheet takes precedence.
Categories and hazard statements
| Code | Category | Statement | Pictogram | Signal word |
|---|---|---|---|---|
| H360 | Category 1, 1A, 1B | May damage fertility or the unborn child | GHS08 | Danger |
| H360F | Category 1, 1A, 1B | May damage fertility | GHS08 | Danger |
| H360D | Category 1, 1A, 1B | May damage the unborn child | GHS08 | Danger |
| H360FD | Category 1, 1A, 1B | May damage fertility; May damage the unborn child | GHS08 | Danger |
| H360Fd | Category 1, 1A, 1B | May damage fertility; Suspected of damaging the unborn child | GHS08 | Danger |
| H360Df | Category 1, 1A, 1B | May damage the unborn child; Suspected of damaging fertility | GHS08 | Danger |
| H361 | Category 2 | Suspected of damaging fertility or the unborn child | GHS08 | Warning |
| H361f | Category 2 | Suspected of damaging fertility | GHS08 | Warning |
| H361d | Category 2 | Suspected of damaging the unborn child | GHS08 | Warning |
| H361fd | Category 2 | Suspected of damaging fertility; Suspected of damaging the unborn child | GHS08 | Warning |
Chemicals with reproductive toxicity hazard codes
Chemicals in our database whose primary classification includes any current Reproductive toxicity code (H360, H360F, H360D, H360FD, H360Fd, H360Df, H361, H361f, H361d, H361fd).
19 chemicals in our database. Classification comes from each chemical's primary GHS source, so a supplier's SDS may differ.
Reproductive toxicity: frequently asked questions
What is the GHS hazard class "Reproductive toxicity"?
Reproductive toxicity covers adverse effects on sexual function and fertility in adults, and on the development of offspring. Substances are categorized by how strong the evidence is that they harm fertility or the unborn child.
Which hazard statements belong to Reproductive toxicity?
The current hazard statements for this class are H360, H360F, H360D, H360FD, H360Fd, H360Df, H361, H361f, H361d, H361fd.
Which pictograms and signal words are used for Reproductive toxicity?
Pictograms: GHS08 (Health Hazard). Signal words: Danger or Warning, depending on the category.
What should I do when working with a reproductive toxicity hazard?
Obtain special instructions before use, do not handle until all safety precautions are understood, use the protective equipment the SDS names, and talk to your employer or occupational health professional before working with the material if you are pregnant or planning a pregnancy.
https://pubchem.ncbi.nlm.nih.gov/ghs/ghscode_10.txt (UN GHS Revision 10, retrieved 2026-10-12)