Glossary / Health hazards
Reproductive toxicant
A reproductive toxicant is a substance that can damage sexual function or fertility in adults, or harm the development of offspring before or after birth. The GHS class also covers effects on or through lactation.
Explanation
Reproductive toxicity is a broad class. One branch covers adult reproductive effects, such as reduced sperm quality, disrupted cycles or lower fertility. Another covers developmental effects in the child, which overlap with teratogenic effects but also include altered growth, functional deficits and loss of the pregnancy.
Under GHS and HazCom the class has Category 1A and 1B for known or presumed toxicants and Category 2 for suspected ones. A separate additional category exists for effects on or via lactation. Hazard statements run from H360 for the most serious categories to H361 for suspected effects, with letters indicating whether fertility, the unborn child or both are of concern.
Both men and women can be affected, so reproductive hazards are not only a concern for pregnant workers. Some substances, such as certain metals and solvents, have a long history of linkage to reproductive harm, and the label will state whether the evidence concerns fertility, development or both.
Because injuries can be subtle and delayed, controls should aim at lower exposure for all workers. Programs that single out some workers can create legal problems and still leave others exposed.
What to do and watch for
- Check the H360 and H361 letter suffixes to see whether fertility, development or both are in question.
- Prefer engineering controls, such as enclosure and local exhaust, to reduce airborne exposure.
- Keep contaminated work clothing out of the home and wash hands before eating or drinking.
Where it appears on an SDS
- Section 2: Hazard identification. The reproductive toxicity category, hazard statement and health hazard pictogram are listed with the other health classifications.
- Section 11: Toxicological information. The summary of fertility and development studies, and any lactation concern, appears here.
SDS content and wording vary by supplier. This page is general reference and does not replace the current SDS for your product.